Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Potassium Iodide → 4-[4-(methylthio)phenyl]tetrahydro-2H-pyran-4-carbonitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Potassium Iodide | HCID 4875 | — |
| 반응물 | Bis(2-bromoethyl) ether | HCID 21521 | — |
| 반응물 | Sodium hydride | HCID 24758 | — |
| 반응물 | 2-(4-(Methylthio)phenyl)acetonitrile | HCID 2760087 | — |
| 생성물 | 4-[4-(methylthio)phenyl]tetrahydro-2H-pyran-4-carbonitrile | HCID 68576613 | 77% |
반응 단계
The title compound (5.5 g, 77%, solid after trituration in pentane) was prepared using 4-(methylthio)phenylacetonitrile, bis(2-bromoethyl)ether, sodium hydride and potassium iodide similarly to the procedure used for intermediate 56. Microanalysis: Found: C, 66.62; H, 6.46; N, 5.97%. C13H15NOS requires C, 66.92; H, 6.48; N, 6.00%.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07456164B2 |
| 출처 데이터셋 | uspto-grants-2008_11 |
| ORD ID | ord-d5f7c07a194b453e8a04f9ba24e4bd52 |
| 출처 메모 | uspto-grants-2008_11 |