Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2,6-Difluorobenzoyl chloride → N-(2,6-difluorobenzoyl)-L-tyrosine ethyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2,6-Difluorobenzoyl chloride | HCID 87438 | — |
| 반응물 | Tyrosine ethyl ester hydrochloride | HCID 2724939 | — |
| 생성물 | N-(2,6-difluorobenzoyl)-L-tyrosine ethyl ester | HCID 66843057 | — |
반응 단계
L-Tyrosine ethyl ester hydrochloride (10.0 g) was acylated with 2,6-difluorobenzoyl chloride in a similar manner as described in Example 1-(5) to give N-(2,6-difluorobenzoyl)-L-tyrosine ethyl ester (13.2 g). mp. 149-150° C.; IR (Nujol) 3424, 3277, 1721, 1660, 1624 cm−1; MS (APCI) m/z 350 (M+H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07456217B2 |
| 출처 데이터셋 | uspto-grants-2008_11 |
| ORD ID | ord-36aef04db34843dc9c495520e2c6bf7b |
| 출처 메모 | uspto-grants-2008_11 |