Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Diisopropylethylamine → Benzodiazepinesuccinamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Diisopropylethylamine | HCID 81531 | — |
| 반응물 | Benzodiazepine | HCID 134664 | — |
| 반응물 | HCID 131723749 | HCID 131723749 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | Benzodiazepinesuccinamide | HCID 136334626 | — |
반응 단계
Following the procedures described for the synthesis of 11, diallylsuccinamide intermediate 16 was prepared from 14 in reasonable yield. 14 (2.59, 5.9 mmol), p-chloro-BZD (2.34 g, 6.2 mmol) and DIPEA (1 ml, 5.8 mmol) in 30 ml DMF was heated to 40-50 degree overnight.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07456278B2 |
| 출처 데이터셋 | uspto-grants-2008_11 |
| ORD ID | ord-2f787a2ae6ec41138582c97c2046094a |
| 출처 메모 | uspto-grants-2008_11 |