Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 3-[3-(4-Methoxyphenyl)propyl]glutaric acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | 1,2-Dimethoxyethane | HCID 8071 | — |
| 반응물 | Cyanoacetic acid | HCID 9740 | — |
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | 4-(4-Methoxyphenyl)butanal | HCID 10487555 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 3-[3-(4-Methoxyphenyl)propyl]glutaric acid | HCID 20528827 | — |
반응 단계
4-(4-Methoxyphenyl)butyraldehyde (5.34 g) is reacted with cyanoacetic acid (5.15 g) and sodium hydroxide (2.74 g) in a mixture of glyme (50 ml) and water (60 ml). The mixture is treated with hydrochloric acid and processed as described in Example 2A to afford the title compound (2.1 g) which on crystallization from ethyl acetate-chloroform-hexane had a melting point of 71°-73° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04221725 |
| 출처 데이터셋 | uspto-grants-1980_09 |
| ORD ID | ord-343353e5d2dc4a2a924c7fd14af0282b |
| 출처 메모 | uspto-grants-1980_09 |