Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrogen Bromide → 2-Phenyl-2-cyclohexen-1-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrogen Bromide | HCID 260 | — |
| 반응물 | 2-Bromo-6-phenylcyclohexanone | HCID 12779129 | — |
| 용매 | Butyl ether | HCID 8909 | — |
| 생성물 | 2-Phenyl-2-cyclohexen-1-one | HCID 1201401 | 80% |
반응 단계
A suspension of 4.97 g (19.6 mmole) of 2-bromo-6-phenylcyclohexanone in 120 mL of di-n-butyl ether was heated at 175° C. for 7 hours, at which point evolution of gaseous HBr had essentially ceased. The mixture was concentrated in vacuo and the residue purified by flash chromatography with 75:25 methylene chloride: hexanes to provide 2.69 g (80%) of a white solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05387595 |
| 출처 데이터셋 | uspto-grants-1995_02 |
| ORD ID | ord-edfe22590e604754beb43689d11c139e |
| 출처 메모 | uspto-grants-1995_02 |