1,4-Naphthoquinone → HCID 14614968, 화합물

HRID 273910노트

반응식

HRID 273910 반응식
[C:1]1(=[O:12])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[C:4](=[O:11])[CH:3]=[CH:2]1.[CH:13]([NH:17][C:18](=[O:27])[O:19][CH2:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)=[CH:14][CH:15]=[CH2:16]>C1(C)C=CC=CC=1.C1(C=CC(O)=CC=1)O>[CH2:20]([O:19][C:18]([NH:17][CH:13]1[CH:2]2[CH:3]([C:4](=[O:11])[C:5]3[C:10]([C:1]2=[O:12])=[CH:9][CH:8]=[CH:7][CH:6]=3)[CH2:16][CH:15]=[CH:14]1)=[O:27])[C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1

참가 물질

5

반응물 2

HCID 85301,4-NaphthoquinoneHCID 329894HCID 329894, 화합물

생성물 1

HCID 14614968HCID 14614968, 화합물수율 98.6%

시약·촉매·용매 2

HCID 785Hydroquinone촉매HCID 1140Toluene용매

반응 조건

온도
25 °C

실험 절차

3.16 g of 1,4-naphthoquinone, 4.48 g of benzyl N-butadienylcarbamate and 50 mg of hydroquinone were dissolved in 100 ml of toluene and stirred at 25° C. for 8 hours and the solution was then concentrated in vacuo. The residue was taken up in chloroform, the solution was filtered through silica gel and the filtrate was concentrated in vacuo. 7.12 g of 1-benzyloxycarbonylamino-1,4,4a,9a-tetrahydroanthraquinone (93% pure; 92% of theory) were obtained.

후처리

  1. concentrationthe solution was then concentrated in vacuo
  2. filtrationthe solution was filtered through silica gel
  3. concentrationthe filtrate was concentrated in vacuo

출처 및 근거

ORD 기록
ord-be620bcbb5b1487b9e47685ab899461e
출처 데이터셋
uspto-grants-1995_02
특허 번호
US05387704

반응 노트

불러오는 중…