참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Benzoic acid, 3-(chlorosulfonyl)- | HCID 77641 | — |
| 반응물 | 2-(Chlorosulfonyl)benzoic acid | HCID 14474464 | — |
| 용매 | O-Xylene | HCID 7237 | — |
| 생성물 | Benzoic acid, 3-sulfo- | HCID 8477 | 95.6% |
반응 단계
300 g of 3-(chlorosulfonyl)benzoic acid containing 38.8% water (corresponding to 183.6 g (0.83 mol) of 100% chlorosulfonylbenzoic acid) are admixed with 150 g of water and heated at 100° C. for 1 hour. Then 600 g of xylene are added dropwise over 1 hour and a total of 260 ml of water are azeotropically distilled off with xylene. The reaction mixture is cooled and the precipitate is filtered off with suction. After drying at 100° C./100 torr (13.16 kPa) 164.7 g of 3-sulfobenzoic acid are obtained, the purity determined by titration being 97.7%; this corresponds to a yield of 95.6%.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US05387711 |
|---|
| 출처 데이터셋 | uspto-grants-1995_02 |
|---|
| ORD ID | ord-5c21ac4fce2b41ce973bccab5db1a867 |
|---|
| 출처 메모 | uspto-grants-1995_02 |
|---|
