Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(RS)-Salsolinol → alpha-(3,4-Dimethoxyphenyl)-3,4-dihydro-6,7-dihydroxy-1-methyl-alpha-[(4-methylphenyl)thio]-2(1H)-isoquinoline-pentanenitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (RS)-Salsolinol | HCID 54456 | — |
| 반응물 | alpha-(3-Chloropropyl)-3,4-dimethoxy-alpha-[(4-methylphenyl)-thio]benzeneacetonitrile | HCID 10738259 | — |
| 생성물 | alpha-(3,4-Dimethoxyphenyl)-3,4-dihydro-6,7-dihydroxy-1-methyl-alpha-[(4-methylphenyl)thio]-2(1H)-isoquinoline-pentanenitrile | HCID 10839653 | 18,336.6% |
반응 단계
The procedure of Example 3 is repeated using 1.0 g of α-(3-chloropropyl)-3,4-dimethoxy-α-[(4-methylphenyl)thio]benzeneacetonitrile and 0.76 g of 1-methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline. This affords 0,253 g of the desired product as a beige gum.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05387685 |
| 출처 데이터셋 | uspto-grants-1995_02 |
| ORD ID | ord-8521c75ae97f43b082438604cb2efbcb |
| 출처 메모 | uspto-grants-1995_02 |