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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 274077생성일: 2026년 10월 26일

Cinchonine → Cinchonine

https://huagongshe.com/reaction/274077

반응식

참여 물질

역할이름HCID투입량
반응물CinchonineHCID 90454—
반응물4-Acetylamino-5-(3-methoxyphenyl)valeric acidHCID 20094784—
용매1,4-DioxaneHCID 31275—
생성물CinchonineHCID 90454106.4%
생성물(S)-4-acetylamino-5-(3-methoxyphenyl)valeric acidHCID 54405639—

반응 단계

A mixture of 4-acetylamino-5-(3-methoxyphenyl)valeric acid (151 mg) and (+)-cinchonine (110 mg) in 1,4-dioxane (2.6 ml) was refluxed and the solution was allowed to cool. The resulting precipitates were collected by filtration and dried to give a salt of (S)-4-acetylamino-5-(3-methoxyphenyl)valeric acid and (+)-cinchonin (117 mg). This compound was recrystallized from 1,4-dioxane to give the pure salt (61 mg).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US05387710
출처 데이터셋uspto-grants-1995_02
ORD IDord-1c230b43ee81457ea588668951a8d813
출처 메모uspto-grants-1995_02