Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Cinchonine → Cinchonine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Cinchonine | HCID 90454 | — |
| 반응물 | 4-Acetylamino-5-(3-methoxyphenyl)valeric acid | HCID 20094784 | — |
| 용매 | 1,4-Dioxane | HCID 31275 | — |
| 생성물 | Cinchonine | HCID 90454 | 106.4% |
| 생성물 | (S)-4-acetylamino-5-(3-methoxyphenyl)valeric acid | HCID 54405639 | — |
반응 단계
A mixture of 4-acetylamino-5-(3-methoxyphenyl)valeric acid (151 mg) and (+)-cinchonine (110 mg) in 1,4-dioxane (2.6 ml) was refluxed and the solution was allowed to cool. The resulting precipitates were collected by filtration and dried to give a salt of (S)-4-acetylamino-5-(3-methoxyphenyl)valeric acid and (+)-cinchonin (117 mg). This compound was recrystallized from 1,4-dioxane to give the pure salt (61 mg).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05387710 |
| 출처 데이터셋 | uspto-grants-1995_02 |
| ORD ID | ord-1c230b43ee81457ea588668951a8d813 |
| 출처 메모 | uspto-grants-1995_02 |