2-Chloroethyl isocyanate → 2-(2-Oxazolin-2-ylamino)-isoindoline

HRID 27417

반응식

HRID 27417 반응식
Cl[CH2:2][CH2:3][N:4]=[C:5]=[O:6].[NH2:7][N:8]1[CH2:16][C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[CH2:9]1>C1(C)C=CC=CC=1>[O:6]1[CH2:2][CH2:3][N:4]=[C:5]1[NH:7][N:8]1[CH2:16][C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[CH2:9]1

참가 물질

4

반응물 2

HCID 160352-Chloroethyl isocyanateHCID 127356181,3-Dihydro-2H-isoindol-2-amine

생성물 1

HCID 233429342-(2-Oxazolin-2-ylamino)-isoindoline

시약·촉매·용매 1

HCID 1140Toluene용매2회

실험 절차

3.2 ml of (0.027 M) chlorethyl isocyanate in 15 ml of toluene are added dropwise to 5 g of (0.027 M) 2-amino-isoindoline in 100 ml toluene at a temperature of 20° to 30° C. After 1 hour, the precipitate is sucked off, washed with toluene and dried.

후처리

  1. washwashed with toluene
  2. customdried

출처 및 근거

ORD 기록
ord-6e35732ca4e04b0291a26a336ee10396
출처 데이터셋
uspto-grants-1980_09
특허 번호
US04221798

연결된 노트

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