Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Diethylformamide → 2-Amino-6-chloropurine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Diethylformamide | HCID 12051 | — |
| 반응물 | 1-Piperidinecarboxaldehyde | HCID 17429 | — |
| 반응물 | 2-Diethylaminomethyleneamino-6-chloropurine | HCID 53860168 | — |
| 반응물 | 2-Piperidinomethyleneamino-6-chloropurine | HCID 53979998 | — |
| 생성물 | 2-Amino-6-chloropurine | HCID 5360349 | — |
반응 단계
The reaction is carried out in the same manner as in Example 2 except that N,N-diethylformamide or N-formylpiperidine is used in the place of N,N-dimethylformamide to yield, respectively, a crystal of 2-diethylaminomethyleneamino-6-chloropurine or 2-piperidinomethyleneamino-6-chloropurine as an intermediate for further synthesis. A further treatment is carried out in the same manner as in Example 2 on these crystals to yield a white crystal of 2-amino-6-chloropurine.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05389637 |
| 출처 데이터셋 | uspto-grants-1995_02 |
| ORD ID | ord-98a2bfc10ace44b1b5056c5010171480 |
| 출처 메모 | uspto-grants-1995_02 |