Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Thioacetamide → 5-(2-Methyl-4-thiazolyl)-3-nitropyrocatechol hydrobromide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Thioacetamide | HCID 2723949 | — |
| 반응물 | 2-Bromo-1-(3,4-dihydroxy-5-nitro-phenyl)-ethanone | HCID 21845596 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 5-(2-Methyl-4-thiazolyl)-3-nitropyrocatechol hydrobromide | HCID 21459102 | — |
반응 단계
A mixture of 3.12 g of 2-bromo-3',4'-dihydroxy-5'-nitroacetophenone and 849.3 mg of thioacetamide are heated to boiling under reflux for 18 hours in 40 ml of ethanol. After cooling, the crystals are filtered under suction and recrystallized from methanol/isopropanol. There is obtained 5-(2-methyl-4-thiazolyl)-3-nitropyrocatechol hydrobromide of m.p. 280°-282°.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05389653 |
| 출처 데이터셋 | uspto-grants-1995_02 |
| ORD ID | ord-a5b3873195ae4150b60aefa9620af38f |
| 출처 메모 | uspto-grants-1995_02 |