Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Aminothiazole → 5-(Imidazo[2,1-b]thiazol-6-yl)-3-nitropyrocatechol hydrobromide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Aminothiazole | HCID 2155 | — |
| 반응물 | 2-Bromo-1-(3,4-dihydroxy-5-nitro-phenyl)-ethanone | HCID 21845596 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 5-(Imidazo[2,1-b]thiazol-6-yl)-3-nitropyrocatechol hydrobromide | HCID 21459143 | — |
반응 단계
A mixture of 2.78 g of 2-bromo-3',4'-dihydroxy-5'-nitroacetophenone, 1.01 g of 2-aminothiazole and 40 ml of ethanol is heated to boiling under reflux for 23 hours. The reaction mixture is then cooled to room temperature and the crystals are removed by filtration under suction. There is obtained 5-(imidazo[2,1-b]thiazol-6-yl)-3-nitropyrocatechol hydrobromide of m.p. 286°-28820 (from methanol).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05389653 |
| 출처 데이터셋 | uspto-grants-1995_02 |
| ORD ID | ord-5e364a4d4d274bdaae63883439bcc2e6 |
| 출처 메모 | uspto-grants-1995_02 |