Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Thionicotinamide → 3-Nitro-5-[2-(3-pyridyl)-4-thiazolyl]pyrocatechol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Thionicotinamide | HCID 737155 | — |
| 반응물 | 2-Bromo-1-(3,4-dihydroxy-5-nitro-phenyl)-ethanone | HCID 21845596 | — |
| 생성물 | 3-Nitro-5-[2-(3-pyridyl)-4-thiazolyl]pyrocatechol | HCID 21459199 | — |
반응 단계
A suspension of 2.91 g of 2-bromo-3',4'-dihydroxy-5'-nitroacetophenone is treated with 1.31 g of thionicotinamide in 50 ml of alcohol and heated to boiling under reflux for 2 hours. After cooling to room temperature the crystals are filtered under suction and recrystallized from N,N-dimethylformamide/alcohol. There is obtained 3-nitro-5-[2-(3-pyridyl)-4-thiazolyl]pyrocatechol of m.p. 279°-281°.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05389653 |
| 출처 데이터셋 | uspto-grants-1995_02 |
| ORD ID | ord-9e82f967678f416c958045fed731d3fa |
| 출처 메모 | uspto-grants-1995_02 |