Ammonium Chloride → (3-Bromopropyl)methyldibutyltin

HRID 27457노트

반응식

HRID 27457 반응식
[CH2:1]([Mg]Br)[CH2:2][CH2:3][CH3:4].[Br:7][CH2:8][CH2:9][CH2:10][Sn:11](Br)(Br)[CH3:12].[NH4+].[Cl-]>C(OCC)C>[Br:7][CH2:8][CH2:9][CH2:10][Sn:11]([CH3:12])([CH2:1][CH2:2][CH2:3][CH3:4])[CH2:1][CH2:2][CH2:3][CH3:4]

참가 물질

5

반응물 3

HCID 25517Ammonium ChlorideHCID 86737202(3-Bromopropyl)methyltin dibromideHCID 178418682HCID 178418682, 화합물

생성물 1

HCID 86737201(3-Bromopropyl)methyldibutyltin수율 88%

시약·촉매·용매 1

HCID 3283Diethyl Ether용매2회

실험 절차

A solution of 115 ml of 2.7 N butylmagnesium bromide in diethyl ether was added in about one hour to a solution of 62.5 g (0.15 mol) of (3-bromopropyl)methyltin dibromide in 200 ml of diethyl ether. After reflux for 1 h the mixture was treated with a saturated aqueous solution of NH4Cl and distilled to give 48.79 g (88%) of (3-bromopropyl)methyldibutyltin; b.p. 88°-90° C./0.1 mm Hg, nD20 =1.5001.

후처리

  1. temperatureAfter reflux for 1 h the mixture
  2. distillationdistilled

출처 및 근거

ORD 기록
ord-6d2127166d5c42d985bc9f775c1d520e
출처 데이터셋
uspto-grants-1980_09
특허 번호
US04221811

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