Propionyl chloride → HCID 23343022, 화합물

HRID 27472노트

반응식

HRID 27472 반응식
[C:1]([C:4]1[CH:22]=[CH:21][C:7]([C:8]([NH:10][C:11]2[CH:19]=[C:18]([NH2:20])[CH:17]=[CH:16][C:12]=2[C:13]([OH:15])=[O:14])=[O:9])=[CH:6][CH:5]=1)([OH:3])=[O:2].[C:23](Cl)(=[O:26])[CH2:24][CH3:25]>C(O)(C)C>[C:1]([C:4]1[CH:5]=[CH:6][C:7]([C:8]([NH:10][C:11]2[CH:19]=[C:18]([NH:20][C:23](=[O:26])[CH2:24][CH3:25])[CH:17]=[CH:16][C:12]=2[C:13]([OH:15])=[O:14])=[O:9])=[CH:21][CH:22]=1)([OH:3])=[O:2]

참가 물질

4

반응물 2

HCID 62324Propionyl chlorideHCID 233430382-(4-Carboxybenzamido)-4-aminobenzoic acid

생성물 1

HCID 23343022HCID 23343022, 화합물수율 62%

시약·촉매·용매 1

HCID 3776Isopropanol용매

실험 절차

The procedure of Example 4 was repeated to react 2-(4-carboxybenzamido)-4-aminobenzoic acid with propionyl chloride, and the reaction product was treated as in Example 4 except that isopropyl alcohol was used as a solvent for recrystallization. The product obtained was a 62% yield of 2-(4-carboxybenzamido)-4-propionamidobenzoic acid having a melting point in the range of from 284° to 286° C. (decompose).

후처리

  1. customwas used as a solvent for recrystallization
  2. customThe product obtained

출처 및 근거

ORD 기록
ord-47e35bb137994dbc9816a068225b13f4
출처 데이터셋
uspto-grants-1980_09
특허 번호
US04221814

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