Water → 2,2-Dimethyl-3-phenylpropanoic acid

HRID 274821

반응식

HRID 274821 반응식
[CH3:1][C:2]([CH3:15])([CH2:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)[C:3]([O:5]CC)=[O:4].[OH-].[K+].O>CO>[CH3:1][C:2]([CH3:15])([CH2:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)[C:3]([OH:5])=[O:4]

참가 물질

5

반응물 3

HCID 962WaterHCID 14797Potassium HydroxideHCID 4684633Ethyl 2,2-dimethyl-3-phenylpropanoate

생성물 1

HCID 218802,2-Dimethyl-3-phenylpropanoic acid

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

A solution of 1 g (20 mmol) of ethyl 2,2-dimethyl-3-phenylpropionate (stage 1) and 3.5 g (61 mmol) of potassium hydroxide in 15 ml of methanol was heated under reflux for 2 hours. Thereafter, 50 ml of water were added and the mixture was extracted twice with ether. The aqueous phase was acidified with concentrated hydrochloric acid and extracted again with ether, the organic phase was dried over magnesium sulfate and the solvent was striped off in vacuo.

후처리

  1. temperatureunder reflux for 2 hours
  2. extractionthe mixture was extracted twice with ether
  3. extractionextracted again with ether
  4. dry with materialthe organic phase was dried over magnesium sulfate

출처 및 근거

ORD 기록
ord-efca2393aca843ff81caf973a753a5b9
출처 데이터셋
uspto-grants-1995_02
특허 번호
USRE034865

연결된 노트

불러오는 중…