Thionyl Chloride → 2,3,5-Trichlorophenylacetyl chloride

HRID 274834노트

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HRID 274834 반응식
[Cl:1][C:2]1[C:7]([Cl:8])=[CH:6][C:5]([Cl:9])=[CH:4][C:3]=1[CH2:10][C:11]([OH:13])=O.S(Cl)([Cl:16])=O>C(Cl)(Cl)(Cl)Cl>[Cl:1][C:2]1[C:7]([Cl:8])=[CH:6][C:5]([Cl:9])=[CH:4][C:3]=1[CH2:10][C:11]([Cl:16])=[O:13]

참가 물질

4

반응물 2

HCID 24386Thionyl ChlorideHCID 186876252,3,5-Trichlorophenylacetic acid

생성물 1

HCID 214781102,3,5-Trichlorophenylacetyl chloride

시약·촉매·용매 1

HCID 5943Carbon Tetrachloride용매

실험 절차

A suspension of 6.0 grams (0.023 mole) of 2,3,5-trichlorophenylacetic acid in about 125 mL of carbon tetrachloride was stirred, and 5 mL of thionyl chloride was added. The reaction mixture was then warmed to reflux, where it was stirred for about 30 minutes. After this time the reaction mixture was concentrated under reduced pressure, yielding 6.4 grams of 2,3,5-trichlorophenylacetyl chloride.

후처리

  1. temperatureThe reaction mixture was then warmed
  2. temperatureto reflux
  3. stirringwhere it was stirred for about 30 minutes
  4. concentrationAfter this time the reaction mixture was concentrated under reduced pressure

출처 및 근거

ORD 기록
ord-48b2e19bc4d145b29dcd0b1020a8fc77
출처 데이터셋
uspto-grants-1995_02
특허 번호
US05391541

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