Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium hydride → HCID 21478104, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium hydride | HCID 24758 | — |
| 반응물 | Ethyl 3-amino-4,4,4-trifluoro-2-butenoate | HCID 136209 | — |
| 반응물 | HCID 21478106 | HCID 21478106 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | HCID 21478104 | HCID 21478104 | 55.8% |
반응 단계
By the method of Example 1, Step G, 19.67 grams (0.080 mole) of 2,3-dichloro-5-nitrophenylmethyl isocyanate, 2.102 grams (0.088 mole) of sodium hydride, and 14.59 grams (0.080 mole) of ethyl 3-amino-4,4,4-trifluoro-2-butenoate were reacted in 80 mL of N,N-dimethylformamide, yielding 17.14 grams of 3-(2,3-dichloro-5-nitrophenylmethyl)-6-trifluoromethyluracil as a brown solid. The NMR spectrum was consistent with the proposed structure. This reaction was repeated.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05391541 |
| 출처 데이터셋 | uspto-grants-1995_02 |
| ORD ID | ord-243f72489f334deba3a8e63976ee3ebc |
| 출처 메모 | uspto-grants-1995_02 |