Water → HCID 20088899, 화합물

HRID 274877

반응식

HRID 274877 반응식
[CH3:1][O:2][C:3]1[CH:8]=[C:7]([O:9][CH3:10])[N:6]=[C:5]([O:11][C:12]2[C:13]([C:21]([O-:23])=[O:22])=[N:14][C:15]([N:18]([CH3:20])[CH3:19])=[CH:16][CH:17]=2)[N:4]=1.[K+].[CH2:25]([O:27][C:28]([O:30][CH:31](Cl)[CH3:32])=[O:29])[CH3:26].O>CN(C)C=O>[CH3:10][O:9][C:7]1[CH:8]=[C:3]([O:2][CH3:1])[N:4]=[C:5]([O:11][C:12]2[C:13]([C:21]([O:23][CH:25]([O:27][C:28]([O:30][CH2:31][CH3:32])=[O:29])[CH3:26])=[O:22])=[N:14][C:15]([N:18]([CH3:19])[CH3:20])=[CH:16][CH:17]=2)[N:6]=1

참가 물질

5

반응물 3

HCID 962WaterHCID 162095Carbonic acid, 1-chloroethyl ethyl esterHCID 23710069HCID 23710069, 화합물

생성물 1

HCID 20088899HCID 20088899, 화합물

시약·촉매·용매 1

HCID 6228Dimethylformamide용매

실험 절차

2.0 g (5.6 mmol) of potassium 3-(4,6-dimethoxypyrimidin-2-yl)oxy-6-dimethylaminopicolinate and 0.8 g (5.7 mmol) of 1-(ethoxycarbonyloxy) ethylchloride were suspended in 5 ml of dimethylformamide, and were stirred at room temperature for 6 hours. The reaction mixture was poured into water, and was extracted with ethyl acetate twice. The organic layer was then washed with water and dried, and the solvent was distilled off to obtain a viscous product which was then column-purified to obtain an aimed compound.

후처리

  1. extractionwas extracted with ethyl acetate twice
  2. washThe organic layer was then washed with water
  3. customdried
  4. distillationthe solvent was distilled off
  5. customto obtain a viscous product which
  6. customwas then column-purified

출처 및 근거

ORD 기록
ord-4e6006c90f2948af92b946712e3570a3
출처 데이터셋
uspto-grants-1995_02
특허 번호
US05391537

연결된 노트

불러오는 중…