Triethyl Citrate → 1,2,3-Triethyl 1,2,3-propanetricarboxylate

HRID 275061

반응식

HRID 275061 반응식
[C:1]([O:17][CH2:18][CH3:19])(=[O:16])[CH2:2][C:3]([CH2:10][C:11]([O:13][CH2:14][CH3:15])=[O:12])([C:5]([O:7][CH2:8][CH3:9])=[O:6])O.O1CCCC1.[H][H]>C(O)C>[CH2:2]([C:1]([O:17][CH2:18][CH3:19])=[O:16])[CH:3]([C:5]([O:7][CH2:8][CH3:9])=[O:6])[CH2:10][C:11]([O:13][CH2:14][CH3:15])=[O:12]

참가 물질

5

반응물 3

HCID 6506Triethyl CitrateHCID 8028TetrahydrofuranHCID 178418361HCID 178418361, 화합물

생성물 1

HCID 2210551,2,3-Triethyl 1,2,3-propanetricarboxylate수율 45%

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

400 ml of triethyl citrate were hydrogenated at 175° C. and 10 bar together with 1100 ml of tetrahydrofuran and 60 g of catalyst G (4-mm tablets) until the take-up of hydrogen had ceased. The reaction product was freed from ethanol and distilled under reduced pressure, giving 193 g (45%) of triethyl propane-1,2,3-tricarboxylate.

후처리

  1. customwere hydrogenated at 175° C.
  2. distillationdistilled under reduced pressure

출처 및 근거

ORD 기록
ord-fdfd6c8e013d482092b9552ae9442a80
출처 데이터셋
uspto-grants-1995_02
특허 번호
US05391771

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