Acetyl chloride → Benzoic acid, 3-methoxy-4-methyl-, methyl ester
반응식
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:9]=[CH:10][C:11]=1[CH3:12])[C:6]([OH:8])=[O:7].[C:13](Cl)(=O)C>CO>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:9]=[CH:10][C:11]=1[CH3:12])[C:6]([O:8][CH3:13])=[O:7]참가 물질
4
실험 절차
A solution of 3-methoxy-4-methylbenzoic acid (6.0 g.) in methanol (120 ml.) was treated with acetyl chloride (6 ml.) and stirred for 36 hours. The solution was evaporated. The residue was dissolved in methanol (100 ml.) and the solution evaporated. This procedure was repeated to give methyl 3-methoxy-4-methylbenzoate (6.34 g., 98%) as a colorless oil; NMR: 2.2(s,3H, CH3), 3.9(2s,6H, 2×OCH3), 7.1(d,1H), 7.5 (m,2H).
후처리
- customThe solution was evaporated
- dissolutionThe residue was dissolved in methanol (100 ml.)
- customthe solution evaporated
출처 및 근거
- ORD 기록
- ord-51850e3273114ccbaaa1b8875901bd74
- 출처 데이터셋
- uspto-grants-1995_02
- 특허 번호
- US05391758
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