Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethylene Glycol → 2-(2-Hydroxyethoxymethyl)pyrazine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethylene Glycol | HCID 174 | — |
| 반응물 | Pyrazine, 2-(chloromethyl)- | HCID 170169 | — |
| 반응물 | Sodium | HCID 5360545 | — |
| 생성물 | 2-(2-Hydroxyethoxymethyl)pyrazine | HCID 20567544 | — |
반응 단계
2-Chloromethylpyrazine is reacted with the sodium salt of ethylene glycol to give 2-(2-hydroxyethoxymethyl)pyrazine which is treated with thionyl chloride to give 2-(2-chloroethoxymethyl)pyrazine. Using this intermediate in place of 4-(3-chloropropoxy(methylimidazole in the procedure of Example 22 gives the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04221802 |
| 출처 데이터셋 | uspto-grants-1980_09 |
| ORD ID | ord-738a1d3057c54f41b9c4d43bb5ae35b6 |
| 출처 메모 | uspto-grants-1980_09 |