2-Methylbenzothiazole → 2-Methyl-3-(5-carboxypentyl) benzothiazolium bromide

반응식

[CH3:1][C:2]1[S:3][C:4]2[CH:10]=[CH:9][CH:8]=[CH:7][C:5]=2[N:6]=1.[Br:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][C:17]([OH:19])=[O:18]>>[Br-:11].[CH3:1][C:2]1[S:3][C:4]2[CH:10]=[CH:9][CH:8]=[CH:7][C:5]=2[N+:6]=1[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][C:17]([OH:19])=[O:18]

참가 물질

반응물 2

HCID 84462-Methylbenzothiazole

HCID 202106-Bromohexanoic acid

생성물 1

HCID 229308882-Methyl-3-(5-carboxypentyl) benzothiazolium bromide수율 212.9%

반응 조건

온도: 120 °C

실험 절차

2-methyl benzothiazole (19.5g, 0.1M) and 6-bromohexanoic acid (15.3g, 0.1M) were mixed and heated at 120° C. for 4 hours under continuous agitation. The resulting solid was broken up, ground with ether and then filtered. The filtrate was washed with more ether (250ml) to yield an off-white powder (57.5g).

후처리

filtrationground with ether and then filtered
washThe filtrate was washed with more ether (250ml)

출처 및 근거

ORD 기록: ord-e9b9ffc8121942548db3ebc77f1545c8
출처 데이터셋: uspto-grants-1995_02
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05393654

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