Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-(Trifluoromethyl)phenylhydrazine → 2-(3-Trifluoromethylbenzoyl)nicotinic acid (4-trifluoromethylphenyl)hydrazone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-(Trifluoromethyl)phenylhydrazine | HCID 136200 | — |
| 반응물 | 2-(3-Trifluoromethylbenzoyl)nicotinic acid | HCID 20078895 | — |
| 촉매 | p-Toluenesulfonic acid | HCID 6101 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 2-(3-Trifluoromethylbenzoyl)nicotinic acid (4-trifluoromethylphenyl)hydrazone | HCID 178519560 | 80.7% |
반응 단계
2-(3-Trifluoromethylbenzoyl)nicotinic acid (0.5 g), 4-trifluoromethylphenylhydrazine (0.3 g) and para-toluene sulphonic acid (0.001 g) were stirred in methanol at room temperature for 22 hours. Solvent was evaporated. The residue was triturated in cold toluene then dried to yield the title compound as a beige solid (0.62 g), m.p. 127°-129° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05393730 |
| 출처 데이터셋 | uspto-grants-1995_02 |
| ORD ID | ord-0f21748979904a6cb9e4027cefd1fe85 |
| 출처 메모 | uspto-grants-1995_02 |