Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethanol → n-(5-Amino-2-methoxyphenyl)acetamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethanol | HCID 702 | — |
| 반응물 | 2-Methoxy-5-nitroaniline | HCID 7447 | — |
| 반응물 | AcOH AcOAc | HCID 21895370 | — |
| 촉매 | Adams' catalyst | HCID 345198 | — |
| 용매 | Oxolane--water (1/1) | HCID 21881883 | — |
| 생성물 | n-(5-Amino-2-methoxyphenyl)acetamide | HCID 267867 | — |
반응 단계
2-Methoxy-5-nitroaniline was purchased and acetylated using HOAc/Ac2O in H2O/THF according to known procedures to make 2-methoxy-5-nitroacetanilide. This was reduced using catalytic hydrogenation (PtO2, H2, EtOH) to afford 3-acetamido-4-methoxyaniline which was reacted as described in Examples 1 and 2 to yield the desired glutarimide.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05393735 |
| 출처 데이터셋 | uspto-grants-1995_02 |
| ORD ID | ord-a425c07c7b5d406baa6be5ac9f3e315a |
| 출처 메모 | uspto-grants-1995_02 |