Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-(iodomethyl)-2,3-dihydro-1H-indene → 2-[1-(Indan-2-yl)methyl-1,2,3,6-tetrahydropyridin-4-yl]-1h-indole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-(iodomethyl)-2,3-dihydro-1H-indene | HCID 2763015 | — |
| 반응물 | 2-(pyridin-4-yl)-1H-indole | HCID 2771689 | — |
| 생성물 | 2-[1-(Indan-2-yl)methyl-1,2,3,6-tetrahydropyridin-4-yl]-1h-indole | HCID 18545908 | — |
반응 단계
From 22c and 27a. 1H NMR (CDCl3) d 2.50-2.55 (m, 2H), 2.65 (broad s, 2H), 2.70-2.85 (m, 5H), 3.00-3.15 (m, 2H), 3.25 (d, 2H), 6.05 (broad s, 1H), 6.45 (s, 1H), 7.05 (t, 1H), 7.10-7.25 (m, 5H), 7.30 (d, 1H), 7.55 (d, 1H), 8.10 (broad s, 1H). MS m/z (%): 329 (MH+, 5%), 160 (4%), 131 (4%), 91 (6%), 44 (100%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06352988B2 |
| 출처 데이터셋 | uspto-grants-2002_03 |
| ORD ID | ord-01c81854563344c7b594b1da59bac46e |
| 출처 메모 | uspto-grants-2002_03 |