4-Benzylphenylacetamide → 3-Benzyl-1-cyanomethylbenzene

HRID 276150노트

반응식

HRID 276150 반응식
C(C1C=CC(CC(N)=O)=CC=1)C1C=CC=CC=1.[CH2:18]([C:25]1[CH:26]=[C:27]([CH2:31][C:32]([NH2:34])=O)[CH:28]=[CH:29][CH:30]=1)[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1>>[CH2:18]([C:25]1[CH:26]=[C:27]([CH2:31][C:32]#[N:34])[CH:28]=[CH:29][CH:30]=1)[C:19]1[CH:20]=[CH:21][CH:22]=[CH:23][CH:24]=1

참가 물질

3

반응물 2

HCID 183170054-BenzylphenylacetamideHCID 183170083-Benzylphenylacetamide

생성물 1

HCID 183170103-Benzyl-1-cyanomethylbenzene

실험 절차

The two cyanomethyl intermediates, prepared above, were converted via the H202 conditions of Example 2 to their corresponding crystalline amides: 4-benzylphenylacetamide (93%), melting at 183-84° C. and 3-benzylphenylacetamide (59%), melting at 136-37° C.

후처리

  1. customThe two cyanomethyl intermediates, prepared above,

출처 및 근거

ORD 기록
ord-8c7af49f7cd6464dae35d0276a912c4c
출처 데이터셋
uspto-grants-2002_03
특허 번호
US06353128B1

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