Benzaldehyde → Heptanophenone

HRID 276161

반응식

HRID 276161 반응식
[CH:1](=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.NC1C(C)=CC=CN=1.N[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1.C(O)(=O)C1C=CC=CC=1.C=CCCCC.C1(C)C=CC=CC=1>>[C:1]([C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1)(=[O:8])[CH2:22][CH2:23][CH2:18][CH2:19][CH2:20][CH3:21]

참가 물질

7

반응물 6

HCID 240BenzaldehydeHCID 243Benzoic AcidHCID 1140TolueneHCID 6115AnilineHCID 115971-HexeneHCID 153472-Amino-3-methylpyridine

생성물 1

HCID 74282Heptanophenone

반응 조건

온도
130 °C

실험 절차

Under the same reaction procedure and conditions as in Example 1 (benzaldehyde 0.5 mmol, 2-amino-3-picoline 0.1 mmol, aniline 0.3 mmol, bezoic acid 0.03 mmol, 1-hexene 2.5 mmol, toluene 0.87 mmol), the mixture in a 500 ml pressure reactor was stirred at normal temperature for 2-3 minutes and then various transition metal catalysts as shown in the following table 6 were added to each reactor. While the reactor was stopped with a stopper, the reactants were heated at 130° C. for 1 hour with stirring. After completion of the reaction, gas chromatography was conducted to determine the yields of heptanophenone, products according to various transition metal catalysts. The results are shown in Table 6, below.

후처리

  1. additionwere added to each reactor
  2. stirringwith stirring
  3. customAfter completion of the reaction, gas chromatography

출처 및 근거

ORD 기록
ord-0b2b3a60d24044dfbcbd6ee1f35c0342
출처 데이터셋
uspto-grants-2002_03
특허 번호
US06353139B1

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