Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
6-Chlorothieno[2,3-b]pyridine-2-sulfonyl chloride → HCID 54285997, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 6-Chlorothieno[2,3-b]pyridine-2-sulfonyl chloride | HCID 18176355 | — |
| 반응물 | 3-(3-(S)-Amino-2-oxopyrrolidin-1-ylmethyl)benzonitrile hydrochloride | HCID 22870786 | — |
| 생성물 | HCID 54285997 | HCID 54285997 | — |
반응 단계
The title compound is prepared from 3-(3-(S)-amino-2-oxo-pyrrolidin-1-ylmethyl)-benzonitrile hydrochloride as described in EXAMPLE 1, Part E using 6-chlorothieno[2,3-b]pyridine-2-sulfonyl chloride in place of benzo[b]thiophene-2-sulfonyl chloride. The crude product is purified by column chromatography eluting with a gradient of 10% EtOAc/CH2 Cl2 to 25% EtOAc/CH2Cl2 to afford a white solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05731315 |
| 출처 데이터셋 | uspto-grants-1998_03 |
| ORD ID | ord-3fd33ae5f6e6424f853b83bed699d2ad |
| 출처 메모 | uspto-grants-1998_03 |