Ethanolamine → N-cycloheptylmethyl-N-(2-hydroxyethyl)amine

HRID 276420노트

반응식

HRID 276420 반응식
[OH:1][CH2:2][CH2:3][NH2:4].[CH:5]1([CH2:12]Br)[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7][CH2:6]1>>[CH:5]1([CH2:12][NH:4][CH2:3][CH2:2][OH:1])[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7][CH2:6]1

참가 물질

3

반응물 2

HCID 700EthanolamineHCID 23000753(Bromomethyl)cycloheptane

생성물 1

HCID 18316190N-cycloheptylmethyl-N-(2-hydroxyethyl)amine

실험 절차

2-Hydroxyethylamine was reacted with cycloheptylmethyl bromide according to Method B2a to give N-cycloheptylmethyl-N-(2-hydroxyethyl)amine. The alcohol was reacted with SOCl2 according to Method B7c to give N-cycloheptylmethyl-N-(2-chloroethyl)ammonium chloride. The chloroethylamine was reacted with 2-methoxy-4-nitrophenyl isothiocyanate to give 2-(2-methoxy-4-nitrophenylimino)-3-(cycloheptylmethyl)-1,3-thiazolidine.

출처 및 근거

ORD 기록
ord-bf8f739d8d094c7a976ae690cdbcaa43
출처 데이터셋
uspto-grants-2002_03
특허 번호
US06353006B1

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