Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethanolamine → HCID 178426109, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethanolamine | HCID 700 | — |
| 반응물 | (+)-L-Leucine methyl ester | HCID 65105 | — |
| 반응물 | 3-Chloro-6-isothiocyanatotoluene | HCID 90021 | — |
| 반응물 | L-Leucinol | HCID 111307 | — |
| 생성물 | HCID 178426109 | HCID 178426109 | — |
반응 단계
(1S)-1-(Hydroxymethyl)-3-methylbutylamine was made from (L)-leucine methyl ester as described in Method B1b. The 2-hydroxyethylamine was converted to (1S)-1-(chloromethyl)-3-methylbutanammonium chloride as described in Method B7a. 4-Chloro-2-methylphenyl isothiocyanate was reacted with (1S)-1-(chloromethyl)-3-methylbutanammonium chloride according to Method C1a to give (4S)-2-(4-Chloro-2-methylphenylimino)-4-isobutyl-1,3-thiazolidine. The thiazolidine was reacted with isobutyl bromide according to Method D2a to give (4S)-2-(4-chloro-2-methylphenylimino)-3,4-diisobutyl-1,3-thiazolidine.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06353006B1 |
| 출처 데이터셋 | uspto-grants-2002_03 |
| ORD ID | ord-c4da1592dd674767a820aab616edfc66 |
| 출처 메모 | uspto-grants-2002_03 |