Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Thionyl Chloride → (4S)-2-(4-cyano-2-ethylphenylimino)-4-isobutyl-1,3-thiazolidine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 반응물 | L-Leucinol | HCID 111307 | — |
| 반응물 | 2-Ethyl-4-cyanophenyl isothiocyanate | HCID 18316102 | — |
| 생성물 | (4S)-2-(4-cyano-2-ethylphenylimino)-4-isobutyl-1,3-thiazolidine | HCID 178436590 | — |
반응 단계
(1S)-1-(Hydroxymethyl)-3-methylbutylamine was reacted with SOCl2 followed by 4-cyano-2-ethylphenyl isothiocyanate according to Method C2a to give (4S)-2-(4-cyano-2-ethylphenylimino)-4-isobutyl-1,3-thiazolidine. The thiazolidine was reacted with isobutyl bromide according to Method D2a to give (4S)-2-(4-cyano-2-ethylphenylimino)-3,4-diisobutyl-1,3-thiazolidine.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06353006B1 |
| 출처 데이터셋 | uspto-grants-2002_03 |
| ORD ID | ord-729bc953ecec46e080796b4cb27e7f59 |
| 출처 메모 | uspto-grants-2002_03 |