Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Isobutylene oxide → N-((1S)-1-cyclohexyl-1-ethyl)-N-(2,2-dimethyl-2-hydroxyethyl)amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Isobutylene oxide | HCID 11208 | — |
| 반응물 | (S)-(+)-1-Cyclohexylethylamine | HCID 5325951 | — |
| 생성물 | N-((1S)-1-cyclohexyl-1-ethyl)-N-(2,2-dimethyl-2-hydroxyethyl)amine | HCID 57185870 | — |
반응 단계
(1S)-1-Cyclohexyl-1-ethylamine was reacted with 1,2-epoxy-2-methylpropane according to Method B5b to give N-((1S)-1-cyclohexyl-1-ethyl)-N-(2,2-dimethyl-2-hydroxyethyl)amine. N-((1S)-1-Cyclohexyl-1-ethyl)-N-(2,2-dimethyl-2-hydroxyethyl)amine was reacted with SOCl2 followed by 2-methyl-4-nitrophenyl isothiocyanate according to Method C2f to afford 2-(2-methyl-4-nitrophenylimino)-3-((1S)-1-cyclohexyl-1-ethyl)-5,5-dimethyl-1,3-thiazolidine HCl salt.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06353006B1 |
| 출처 데이터셋 | uspto-grants-2002_03 |
| ORD ID | ord-7a6487b5d3e54efc9fe824e0214264ac |
| 출처 메모 | uspto-grants-2002_03 |