Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Amino-1-naphthalenecarbonitrile → HCID 178510033, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Amino-1-naphthalenecarbonitrile | HCID 42828 | — |
| 반응물 | 4-Isothiocyanato-1-naphthonitrile | HCID 18316068 | — |
| 반응물 | 1-(Chloromethyl)cyclopentan-1-amine hydrochloride | HCID 69992485 | — |
| 생성물 | HCID 178510033 | HCID 178510033 | — |
반응 단계
1-Amino-1-(hydroxymethyl)cyclopentane was synthesized as described in Method B1c. The 2-hydroxyethylamine was reacted with SOCl2 according to Method B7a to give 1-amino-1-(chloromethyl)cyclopentane HCl salt. 1-Amino-4-cyanonaphthalene was converted into 4-cyano-1-naphthyl isothiocyanate according to Method A2a, Step 3. The 2-chloroethylamine was reacted with 4-cyano-1-naphthyl isothiocyanate to Method C1a to give 2-(4-cyano-1-naphthylimino)-1-thia-3-azaspiro[4.4]nonane. The thiazolidine was reacted with isobutyl bromide according to Method D2b to give 3-isobutyl-2-(4-cyano-1-naphthylimino)-1-thia-3-azaspiro[4.4]nonane.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06353006B1 |
| 출처 데이터셋 | uspto-grants-2002_03 |
| ORD ID | ord-eaf32b88be5447f78b5e8b51e477263a |
| 출처 메모 | uspto-grants-2002_03 |