Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Cyclohexane, (bromomethyl)- → 1-(Cyclohexylmethyl)-2-(2-methyl-4-nitrophenylimino)-3-thia-1-azaspiro[4.4]nonane
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Cyclohexane, (bromomethyl)- | HCID 137636 | — |
| 반응물 | 2-(2-Methyl-4-nitrophenylimino)-3-thia-1-azaspiro[4.4]nonane | HCID 178428736 | — |
| 생성물 | 1-(Cyclohexylmethyl)-2-(2-methyl-4-nitrophenylimino)-3-thia-1-azaspiro[4.4]nonane | HCID 18316077 | — |
반응 단계
1-Hydroxymethylcyclopentanamine was prepared according to Method B1c. The 2-hydroxyethylamine was converted to 1-chloromethylcyclopentanamine HCl salt according to Method B7e. 1-Chloromethylcyclopentanamine HCl salt was reacted with 2-methyl-4-nitrophenyl isothiocyanate according to Method C1e to give 2-(2-methyl-4-nitrophenylimino)-3-thia-1-azaspiro[4.4]nonane. The thiazolidine was reacted with cyclohexylmethyl bromide according to Method D2e to give 2-(2-methyl-4-nitrophenylimino)-1-(cyclohexylmethyl)-3-thia-1-azaspiro[4.4]nonane.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06353006B1 |
| 출처 데이터셋 | uspto-grants-2002_03 |
| ORD ID | ord-a9141a16d2ef4855932c48b145f748fa |
| 출처 메모 | uspto-grants-2002_03 |