Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Cyclohexanecarboxylic acid → N-(5-Phenylthiophen-2-yl)cyclohexanecarboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Cyclohexanecarboxylic acid | HCID 7413 | — |
| 반응물 | N-(3-carboxy-methyl-5-phenyl-2-thienyl)-cyclohexane carboxamide | HCID 70592634 | — |
| 반응물 | HCID 178526965 | HCID 178526965 | — |
| 용매 | 2,4,6-Trimethylpyridine | HCID 7953 | — |
| 생성물 | N-(5-Phenylthiophen-2-yl)cyclohexanecarboxamide | HCID 23341601 | — |
반응 단계
This compound (m.p. 174° C.) was prepared from N-(3-carboxy-methyl-5-phenyl-2-thienyl)-cyclohexane carboxamide (31.1 g, 0.1 mole) and LiI.2H2O (48.1 g, 0.32 mole) by refluxing in collidine (125 ml.) according to the procedure of Example 53 (a). This compound was also prepared according to the procedure of Example 53(b), using cyclohexane carboxylic acid as the acylating agent. The products of the two processes were spectrally identical and had a melting point of 175° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04222946 |
| 출처 데이터셋 | uspto-grants-1980_09 |
| ORD ID | ord-fa69975da3e14d579e8308f5c3d04eb7 |
| 출처 메모 | uspto-grants-1980_09 |