Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-ethoxymethylene-2-(1)-naphthyl-5(4H)-oxazolone → [1-(2-Naphthalen-1-yl-5-oxo-oxazol-4-ylidenemethyl)-piperidin-4-yl]-carbamic acid tert-butyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-ethoxymethylene-2-(1)-naphthyl-5(4H)-oxazolone | HCID 356930 | — |
| 반응물 | 4-(N-Boc-amino)piperidine | HCID 723833 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | [1-(2-Naphthalen-1-yl-5-oxo-oxazol-4-ylidenemethyl)-piperidin-4-yl]-carbamic acid tert-butyl ester | HCID 54409055 | — |
반응 단계
To a solution of 4-ethoxymethylene-2-naphthalen-1-yl-4H-oxazol-5-one (6.30 g, 23.7 mmol) in tetrahydrofuran, piperidin-4-yl-carbamic acid tert-butyl ester (4.70 g, 23.7 mmol) was added, and the mixture was stirred at room temperature for 24 h. The reaction mixture was concentrated under reduced pressure to yield [1-(2-naphthalen-1-yl-5-oxo-oxazol-4-ylidenemethyl)-piperidin-4-yl]-carbamic acid tert-butyl ester.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06355641B1 |
| 출처 데이터셋 | uspto-grants-2002_03 |
| ORD ID | ord-70c55eef495c4922a9fbdecab2bff985 |
| 출처 메모 | uspto-grants-2002_03 |