Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Carboxybenzaldehyde → 1,3-Bis(cyclohexylmethyl)-5,6-diaminouracil
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Carboxybenzaldehyde | HCID 12077 | — |
| 반응물 | 6-Amino 1,3-bis(cyclohexylmethyl)-5-nitrosouracil | HCID 22244970 | — |
| 반응물 | HCID 178525288 | HCID 178525288 | — |
| 생성물 | 1,3-Bis(cyclohexylmethyl)-5,6-diaminouracil | HCID 22244975 | — |
반응 단계
1,3-Bis(cyclohexylmethyl)-5,6-diaminouracil was prepared as in part (d) of Example 1 by reduction of 1, 6-amino 1,3-bis(cyclohexylmethyl)-5-nitrosouracil (2.00 g) and immediately condensed with 3-formylbenzoic acid (Aldrich, 1.424 g) by the method of J. Perumattam (Synthetic Commun. 1989, 19: 3367-3370) to give title compound as an off-white solid (2.27 g, 85%), m.p. >250° C.; 1H-NMR (DMSO-d6) consistent with structure.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06355646B1 |
| 출처 데이터셋 | uspto-grants-2002_03 |
| ORD ID | ord-283ff4f419fe44a2a3249bbcbd7e9c5d |
| 출처 메모 | uspto-grants-2002_03 |