3-(3,5-Dichloro-phenyl)-acrylonitrile → 7-(3,5-Dichloro-phenyl)-2-furan-2-yl-[1,2,4]triazolo[1,5-a]pyridin-5-ylamine

반응식

C1(S([CH2:10][C:11]2[N:15]=[C:14]([C:16]3[O:17][CH:18]=[CH:19][CH:20]=3)[NH:13][N:12]=2)(=O)=O)C=CC=CC=1.[Cl:21][C:22]1[CH:23]=[C:24]([CH:29]=[CH:30][C:31]#[N:32])[CH:25]=[C:26]([Cl:28])[CH:27]=1>>[Cl:21][C:22]1[CH:23]=[C:24]([C:29]2[CH:30]=[C:31]([NH2:32])[N:12]3[N:13]=[C:14]([C:16]4[O:17][CH:18]=[CH:19][CH:20]=4)[N:15]=[C:11]3[CH:10]=2)[CH:25]=[C:26]([Cl:28])[CH:27]=1

참가 물질

반응물 2

HCID 687112183-(3,5-Dichloro-phenyl)-acrylonitrile

HCID 178527402HCID 178527402, 화합물

생성물 1

HCID 98410977-(3,5-Dichloro-phenyl)-2-furan-2-yl-[1,2,4]triazolo[1,5-a]pyridin-5-ylamine

실험 절차

The title compound, mp. 257-260° C. and MS m/e (%): 345 (M+H+, 100), was prepared in accordance with the general method of example 1 from 3-benzenesulfonylmethyl-5-furan-2-yl-1H-[1,2,4]triazole and 3-(3,5-dichloro-phenyl)-acrylonitrile

출처 및 근거

ORD 기록: ord-a6501486d90b43ff867ef52e93b81b62
출처 데이터셋: uspto-grants-2002_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06355653B1

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