Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
5-(Hydroxymethyl)furfural → [5-(5-Amino-7-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-yl)-furan-2-yl]-methanol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 5-(Hydroxymethyl)furfural | HCID 237332 | — |
| 반응물 | 4-Bromo-2,6-diaminopyridine | HCID 11435393 | — |
| 반응물 | O-(2,4,6-Trimethylbenzenesulfonyl)hydroxylamine | HCID 11830845 | — |
| 생성물 | [5-(5-Amino-7-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-yl)-furan-2-yl]-methanol | HCID 18313567 | — |
반응 단계
The title compound, MS m/e (%): 311 (M30 +2, 100), was prepared in accordance with the general method of example 63 from 4-bromo-pyridine-2,6-diamine, O-mesitylene-sulfonylhydroxylamine, and 5-hydroxymethyl-furfural. The purification was performed with reversed phase HPLC eluting with an acetonitrile/water gradient.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06355653B1 |
| 출처 데이터셋 | uspto-grants-2002_03 |
| ORD ID | ord-7bfc4a57256541d38bf9500f0c0517cf |
| 출처 메모 | uspto-grants-2002_03 |