3-(5-Chloro-pyridin-2-yl)-acrylonitrile → 7-(5-Chloro-pyridin-2-yl)-2-furan-2-yl-[1,2,4]triazolo[1,5-a]pyridin-5-ylamine

반응식

C1(S([CH2:10][C:11]2[N:15]=[C:14]([C:16]3[O:17][CH:18]=[CH:19][CH:20]=3)[NH:13][N:12]=2)(=O)=O)C=CC=CC=1.[Cl:21][C:22]1[CH:23]=[CH:24][C:25]([CH:28]=[CH:29][C:30]#[N:31])=[N:26][CH:27]=1>>[Cl:21][C:22]1[CH:23]=[CH:24][C:25]([C:28]2[CH:29]=[C:30]([NH2:31])[N:12]3[N:13]=[C:14]([C:16]4[O:17][CH:18]=[CH:19][CH:20]=4)[N:15]=[C:11]3[CH:10]=2)=[N:26][CH:27]=1

참가 물질

반응물 2

HCID 700891653-(5-Chloro-pyridin-2-yl)-acrylonitrile

HCID 178527402HCID 178527402, 화합물

생성물 1

HCID 99048457-(5-Chloro-pyridin-2-yl)-2-furan-2-yl-[1,2,4]triazolo[1,5-a]pyridin-5-ylamine

실험 절차

The title compound, MS m/e (%): 312 (M+H+, 100), was prepared in accordance with the general method of example 1 from 3-benzenesulfonylmethyl-5-furan-2-yl-1H-[1,2,4]triazole and 3-(5-chloro-pyridin-2-yl)-acrylonitrile.

출처 및 근거

ORD 기록: ord-141a8f54131c4339b53599c12b0d486d
출처 데이터셋: uspto-grants-2002_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06355653B1

반응 노트

불러오는 중…