(Z)-3-(6-methoxy-pyridin-3-yl)-acrylonitrile → 2-(2-Fluoro-phenyl)-7-(6-methoxy-pyridin-3-yl)-[1,2,4]triazolo[1,5-a]pyridin-5-ylamine
반응식
C1(S([CH2:10][C:11]2[N:15]=[C:14]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=3[F:22])[NH:13][N:12]=2)(=O)=O)C=CC=CC=1.[CH3:23][O:24][C:25]1[N:30]=[CH:29][C:28](/[CH:31]=[CH:32]\[C:33]#[N:34])=[CH:27][CH:26]=1>>[F:22][C:17]1[CH:18]=[CH:19][CH:20]=[CH:21][C:16]=1[C:14]1[N:15]=[C:11]2[CH:10]=[C:31]([C:28]3[CH:29]=[N:30][C:25]([O:24][CH3:23])=[CH:26][CH:27]=3)[CH:32]=[C:33]([NH2:34])[N:12]2[N:13]=1참가 물질
3
실험 절차
The title compound, MS m/e (%):336(M+H+,100), was prepared in accordance with the general method of example 1 from 3-benzenesulfonylmethyl-5-(2-fluoro-phenyl)-1H-[1,2,4]triazole and (E)/(Z)-3-(6-methoxy-pyridin-3-yl)-acrylonitrile.
출처 및 근거
- ORD 기록
- ord-cdf250fb76584672b04a2c9ab3452146
- 출처 데이터셋
- uspto-grants-2002_03