(Z)-3-pyridin-3-yl-acrylonitrile → 2-Pyridin-2-yl-7-pyridin-3-yl-[1,2,4]triazolo[1,5-a]pyridin-5-ylamine

HRID 277111노트

반응식

HRID 277111 반응식
C1(S([CH2:10][C:11]2[N:12]=[C:13]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][N:17]=3)[NH:14][N:15]=2)(=O)=O)C=CC=CC=1.[N:22]1[CH:27]=[CH:26][CH:25]=[C:24](/[CH:28]=[CH:29]\[C:30]#[N:31])[CH:23]=1>>[N:17]1[CH:18]=[CH:19][CH:20]=[CH:21][C:16]=1[C:13]1[N:12]=[C:11]2[CH:10]=[C:28]([C:24]3[CH:23]=[N:22][CH:27]=[CH:26][CH:25]=3)[CH:29]=[C:30]([NH2:31])[N:15]2[N:14]=1

참가 물질

3

반응물 2

HCID 10441725(Z)-3-pyridin-3-yl-acrylonitrileHCID 178527399HCID 178527399, 화합물

생성물 1

HCID 183136652-Pyridin-2-yl-7-pyridin-3-yl-[1,2,4]triazolo[1,5-a]pyridin-5-ylamine

실험 절차

The title compound, MS m/e (%):288 (M+,100), was prepared in accordance with the general method of example 1 from 2-(5-benzenesulfonylmethyl-2H-[1,2,4]triazol-3-yl)-pyridine and (E)/(Z)-3-pyridin-3-yl-acrylonitrile.

출처 및 근거

ORD 기록
ord-f0b39022f5e541aaa8a2a2cb54e255fd
출처 데이터셋
uspto-grants-2002_03
특허 번호
US06355653B1

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