(Z)-3-(6-chloro-pyridin-3-yl)-acrylonitrile → 7-(6-Chloro-pyridin-3-yl)-2-pyridin-2-yl-[1,2,4]triazolo[1,5-a]pyridin-5-ylamine

HRID 277115노트

반응식

HRID 277115 반응식
C1(S([CH2:10][C:11]2[N:12]=[C:13]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][N:17]=3)[NH:14][N:15]=2)(=O)=O)C=CC=CC=1.[Cl:22][C:23]1[N:28]=[CH:27][C:26](/[CH:29]=[CH:30]\[C:31]#[N:32])=[CH:25][CH:24]=1>>[Cl:22][C:23]1[N:28]=[CH:27][C:26]([C:29]2[CH:30]=[C:31]([NH2:32])[N:15]3[N:14]=[C:13]([C:16]4[CH:21]=[CH:20][CH:19]=[CH:18][N:17]=4)[N:12]=[C:11]3[CH:10]=2)=[CH:25][CH:24]=1

참가 물질

3

반응물 2

HCID 86757855(Z)-3-(6-chloro-pyridin-3-yl)-acrylonitrileHCID 178527399HCID 178527399, 화합물

생성물 1

HCID 183136187-(6-Chloro-pyridin-3-yl)-2-pyridin-2-yl-[1,2,4]triazolo[1,5-a]pyridin-5-ylamine

실험 절차

The title compound, MS m/e (%):323 (M+H+,100), was prepared in accordance with the general method of example 1 from 2-(5-benzenesulfonylmethyl-2H-[1,2,4]triazol-3-yl)-pyridine and (E)/(Z)-3-(6-chloro-pyridin-3-yl)-acrylonitrile.

출처 및 근거

ORD 기록
ord-d538b6ba25f2488393cf6879c124dcde
출처 데이터셋
uspto-grants-2002_03
특허 번호
US06355653B1

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