2-Amino-3-nitrobenzoic acid → 2,3-Diaminobenzoic acid

HRID 278030

반응식

HRID 278030 반응식
[NH2:1][C:2]1[C:10]([N+:11]([O-])=O)=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=[O:5].[H][H]>CO.[Pd]>[NH2:1][C:2]1[C:10]([NH2:11])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=[O:5]

참가 물질

5

반응물 2

HCID 2196332-Amino-3-nitrobenzoic acidHCID 178418361HCID 178418361, 화합물

생성물 1

HCID 1980692,3-Diaminobenzoic acid

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 887Methanol용매

실험 절차

14 g (76.9 mmol) of 2-amino-3-nitrobenzoic acid (1b) were dissolved in 500 ml of methanol, treated with Pd/C, and hydrogenated with hydrogen. After 4 h, the catalyst was filtered off with suction and concentrated. A dark-brown solid was obtained. Yield: 11.67 g (99%).

후처리

  1. filtrationthe catalyst was filtered off with suction
  2. concentrationconcentrated
  3. customA dark-brown solid was obtained

출처 및 근거

ORD 기록
ord-2b175d8949474a819a64b0b78c04ef77
출처 데이터셋
uspto-grants-2002_03
특허 번호
US06358978B1

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