N,N-Bis(2-chloroethyl)benzylamine hydrochloride → Ethyl 1-benzyl-4-{[3-(2-butynyloxy)phenyl]sulfonyl}-4-piperdine carboxylate

참여 물질

역할	이름	HCID	투입량
반응물	N,N-Bis(2-chloroethyl)benzylamine hydrochloride	HCID 2777881	—
반응물	Ethyl{[3-(2-butynyloxy)phenyl]sulfonyl}acetate	HCID 23513876	—
생성물	Ethyl 1-benzyl-4-{[3-(2-butynyloxy)phenyl]sulfonyl}-4-piperdine carboxylate	HCID 17944926	63%

반응 단계

Ethyl 1-benzyl-4-{[3-(2-butynyloxy)phenyl]sulfonyl}-4-piperdine carboxylate was prepared according to the general method as outlined in example 1 (step 6), starting from ethyl{[3-(2-butynyloxy)phenyl]sulfonyl}acetate (3 g, 10.1 mmol) and benzyl-bis-(2-chloro-ethyl) amine hydrochloride (2.88 g, 10.7 mmol); 2.91 g yellow oil. Yield 63%; MS: 456.3 (M+H)+

출처 및 근거

DOI	10.6084/m9.figshare.5104873.v1
특허 번호	US06358980B1
출처 데이터셋	uspto-grants-2002_03
ORD ID	ord-9bfac1a72c1840969ac39e617a38f14d
출처 메모	uspto-grants-2002_03