Acetic Acid → (1S,2R)-(+)-Norephedrine
반응식
C(O)(=O)C.[N+:5]([CH:8]([CH3:17])[CH:9]([C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)[OH:10])([O-])=O>C(O)(C)C>[NH2:5][CH:8]([CH3:17])[CH:9]([C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)[OH:10]참가 물질
4
실험 절차
In the practice of this invention, the 2-nitro-1-phenyl-1-propanol is dissolved in a lower alkyl alcohol, preferably isopropyl alcohol. The mixture is placed in a vessel suitable for high pressure reactions and equipped with agitation means, e.g. a rocking bomb or a stirred bomb. Acetic acid is added to the solution to produce the acetate salt of 2-amino-1-phenyl-1-propanol during the reduction reaction.
후처리
- customThe mixture is placed in a vessel suitable for high pressure reactions
- customequipped with agitation means, e.g. a rocking bomb
출처 및 근거
- ORD 기록
- ord-4cded8dcbfd6476790085eff15e94b2e
- 출처 데이터셋
- uspto-grants-1980_09
- 특허 번호
- US04224246
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