Methyl 2-hydroxybut-3-enoate → Methyl 4-[3-(tert-butyldimethylsilyloxy)phenyl]-2-oxo-butyrate

반응식

[Si:1]([O:8][C:9]1[CH:10]=[C:11](I)[CH:12]=[CH:13][CH:14]=1)([C:4]([CH3:7])([CH3:6])[CH3:5])([CH3:3])[CH3:2].[OH:16][CH:17]([CH:22]=[CH2:23])[C:18]([O:20][CH3:21])=[O:19]>>[Si:1]([O:8][C:9]1[CH:10]=[C:11]([CH2:23][CH2:22][C:17](=[O:16])[C:18]([O:20][CH3:21])=[O:19])[CH:12]=[CH:13][CH:14]=1)([C:4]([CH3:7])([CH3:6])[CH3:5])([CH3:3])[CH3:2]

참가 물질

반응물 2

HCID 545123Methyl 2-hydroxybut-3-enoate

HCID 27572803-(t-Butyldimethylsiloxy)iodobenzene

생성물 1

HCID 22628472Methyl 4-[3-(tert-butyldimethylsilyloxy)phenyl]-2-oxo-butyrate

실험 절차

Methyl 4-[3-(tert-butyldimethylsilyloxy)phenyl]-2-oxo-butyrate was prepared as a yellow oil from 3-(tert-butyldimethylsilyloxy) iodobenzene and methyl 2-hydroxy-3-butenoate.

출처 및 근거

ORD 기록: ord-aa3f6ffcaef64adf90e8c219dafe00f6
출처 데이터셋: uspto-grants-2002_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06359145B1

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