2,3,5-Trimethylphenol → 2,3,5-Trimethylphenyl isopropyl ether

반응식

[Cl-].[CH:2]([O:5][C:6]1[CH:31]=[C:30]([CH3:32])[C:9](C[P+](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)=[C:8]([CH3:33])[C:7]=1[CH3:34])([CH3:4])[CH3:3].CC1C(C)=CC(C)=CC=1O>>[CH:2]([O:5][C:6]1[CH:31]=[C:30]([CH3:32])[CH:9]=[C:8]([CH3:33])[C:7]=1[CH3:34])([CH3:4])[CH3:3]

참가 물질

반응물 2

HCID 127692,3,5-Trimethylphenol

HCID 867359034-Isopropoxy-2,3,6-trimethyl-benzyl-triphenylphosphonium chloride

생성물 1

HCID 202100012,3,5-Trimethylphenyl isopropyl ether

실험 절차

The 4-isopropoxy-2,3,6-trimethyl-benzyl-triphenylphosphonium chloride employed as the starting material is prepared by the procedure described in Example 18 by alkylation of 2,3,5-trimethylphenol to give 2,3,5-trimethylphenyl isopropyl ether (boiling point 115° C./11 mmHg), by haloformylation of the ether obtained to give 4-isopropoxy-2,3,6-trimethyl-benzyl chloride (nD20 =1.5433) and by reaction of the latter compound with triphenylphosphine.

후처리

customis prepared by the procedure

출처 및 근거

ORD 기록: ord-8e06e9ff65114bd5a73d30bc5b41156f
출처 데이터셋: uspto-grants-1980_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04224244

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